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AI enables natural peptide discovery, to unlock your defense against silent aging

What do skincare scientists and artificial intelligence have in common? In this instance, they worked together to develop a naturally sourced ingredient for soothing skin and scalp irritation, specifically addressing the causes of silent aging conditions.

In our everyday lives, the causes of silent aging come from all angles: diet, stress, air pollution, poor sleep habits, lack of exercise and so on. These contributing factors can impact our physical appearance and affects the look and feel of the scalp, skin, and hair.

Seeking solutions, BASF scientists used the power of AI to search for natural and effective peptide solutions. The result? PeptAIde®4.0, a solution based on four peptides unlocked from rice protein with a host of soothing benefits for the skin, hair and scalp.

Published On: 10/21/20

Irritation station

Whatever the cause, silent aging can have a wide range of effects. Low levels of irritation have been shown to cause skin dryness, dehydration and overall discomfort. It ultimately leads to signs of decreasing firmness in the skin.

In the scalp, many people report sensitivity, the appearance of redness as a result of silent aging. It can also create conditions for fragile hair.

Sound relatable? Many people agree, which is why BASF set out to find a natural fix for irritation in the skin, hair and scalp.

AI and BASF: The dream team

The first step to improving signs of premature aging is finding natural ingredients with the right properties. Using predictive discovery through artificial intelligence, we were able to search peptides with specific parameters. This method enables us to find solutions about 10 times faster and increases success factors by 600 times.

With AI’s help, we were able to find and unlock 4 hidden peptides encased in rice protein. The four peptides they identified were chosen for their anti-irritation properties, including protection against aging and soothing benefits.

The discovery led to the development of PeptAIde 4.0, an innovation featuring a natural bioactive peptide network containing these four peptides.

PeptAIde put to the test

Looking for some more? PeptAIde 4.0 helps to support a healthy skin barrier that provides comfort and moisturization to both skin and scalp.

Scalp & Hair:

PeptAIde 4.0 guards the hair, helping to protect natural collagen and elastin components that keep the scalp healthy. This helps to prevent hair “miniaturization” over time. PeptAIde 4.0 helps to block these unhealthy conditions to protect deep in the scalp for a healthy foundation for healthy hair. In addition to these scalp benefits, PeptAIde 4.0 also provides benefits on hair fiber having a 36% hair repair effect on damaged hair.

A clinical test was performed to see PeptAIde 4.0's ability to restore scalp health and reduce hair fiber damage in a rinse off format. PeptAIde 4.0 significantly reduces the appearance of scalp redness by 9% compared to placebo after 21 days of use. It also helps decrease the scalp pH significantly compared to placebo, which supports less scalp sensitivity. After 2 weeks of use, 82% and 69% of consumers agree that the shampoo formulated with 2% PeptAIde 4.0 throughly cleansed while keeping their scalp looking and feeling healthy.

Skin Hydration & Firmness:

A study found PeptAIde 4.0 increases skin moisture and comfort in a body lotion formulated at 2%. In the study, skin flaking and dryness was reduced, and moisturization increased by 33% in as early as one week. Even after consumers discontinued product use for one week, PeptAIde 4.0 had significantly sustained moisturization with 14% more hydration than the placebo.

PeptAIde 4.0 was also found to have body care firming benefits, too, as it effectively improves skin firmness and suppleness. A consumer panel demonstrated that the ingredient provides a body firming effect after as few as two weeks of use — an effect that remained for two weeks after respondents stopped using the product. It was also shown to improve skin elasticity after one month.

Head-to-toe benefits for allover beauty

Who knew AI could help scientists make something so beautiful, not to mention multifunctional? Get in touch with the specialists at BASF Care Creations to learn how we can help you formulate for silent aging claims. We’re here to help.

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